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VQV Signal

OPEN SOURCE SOURCE-BACKED TECHNICAL

Agentic RAG System Matches Patient Profiles to Oncology Trials with LLM Reasoning

The clinical-evidence-navigator is a full-stack agentic retrieval-augmented generation (RAG) system that uses LLM reasoning to match patient profiles to oncology clinical trials on ClinicalTrials.gov. It provides citation-backed outputs and includes an abstention policy for low confidence matches.

Source: GitHub · github.com Published 2026-09-18T21:12:20+00:00 Detected 2026-09-18T21:22:17+00:00
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The clinical-evidence-navigator is a full-stack agentic retrieval-augmented generation (RAG) system that uses LLM reasoning to match patient profiles to oncology clinical trials on ClinicalTrials.gov. It provides citation-backed outputs and includes an abstention policy for low confidence matches.

AI-assisted summary based on the listed source.

Full-stack agentic RAG system (Next.js, FastAPI, pgvector) that matches patient profiles to oncology clinical trials via criterion by criterion LLM reasoning over ClinicalTrials.gov with citation backed outputs and a built in abstention policy for low confidence matches. Stars: 1. Updated repository signal.

This system enhances precision in matching patients to relevant clinical trials by reasoning over trial criteria with large language models, potentially improving trial enrollment and patient outcomes. The built-in abstention policy helps maintain reliability by avoiding uncertain matches.

Signal Strength 92% Technical label SOURCE-BACKED Public Interest 35 Category OPEN SOURCE Reader Depth TECHNICAL

Signal Strength reflects source quality, relevance, freshness and evidence. Public Interest helps organize discovery; it is not proof of truth.

Public Interest components
Recognizable Entity Score 0 Practical Impact Score 36 Novelty Interest Score 70 Consequence Score 50 Curiosity Score 16 Shareability Score 47

VQV surfaced this signal because it is recent, relevant to AI Search, connected to GitHub.